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    QUININE DIHYDROCHLORIDE

WARNING: CAUTION : PLEASE NOTE :
The content or product detailing is not intended to replace advice from your prescribing doctor or healthcare professional. Lavina Pharma is not responsible for such actions by consumers. For any further information about the product please contact +91 22 2783 1455 and we can provide you the details.

QUININE DIHYDROCHLORIDE INJECTION 300 MG / ML

Quinine Dihydrochloride Injection is indicated for the treatment of: - Acute attacks for malaria including attacks due to chloroquinine- resistant or multi-drug resistant strains of Plasmodium falciparum.
Cerebral, Severe or complicated malaria
When vomiting, prevents retention of an orally administered drug.

COMPOSITION

Each ml contains: -
Quinine Dihydrochloride BP …300 mg
Water for Injection BP … q.s


DOSAGE

The dosing and strengths of the dosage form are expressed in terms of quinine dihydrochloride (salt). Usual adult dose and adolescent dose: -
Intravenous (if an infusion pump is available), 7 mg per kg of body weight over thirty minutes followed immediately by 10 mg per kg of body weight diluted in 210 ml per kg isotonic fluid over four hours, repeated every 8 hours until oral treatment can be instituted. Or intravenous (if an infusion pump is not available), 20 mg per kg of body weight over 4 hours followed immediately by 10 mg per kg of body weight diluted in 10 ml per kg isotonic fluid over 4 hours, repeated every 8 hours until oral treatment can be instituted.

SIDE EFFECT
The most commonly reported side-effects of Quinine Dihydrochloride Injection are dryness or cracking of the skin, severe allergic reactions, and irritation.





PRECAUTION
Quinine must be used with caution in patients with atrial fibrillation or other serious heart diseases. Quinine must be stopped immediately if evidence of haemolysis appears. Antimalarial agents and especially quinine, when given for prolonged periods, have been implicated in precipitating black water fever. However, in some cases, deficiency of glucose -6-phosphate.

PRESENTATION
Quinine Dihydrochloride Injection 300 mg is available in 10 ampoules of 2 ml / box.