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LAVIXABAN is indicated to reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation.
Prophylaxis of deep vein
thrombosis hip or knee replacement surgery.
LAVIXABAN 2.5 is a prescription medication containing 2.5 mg of apixaban, an oral anticoagulant. It is used to reduce the risk of stroke and blood clots in patients with atrial fibrillation and to
treat or prevent deep vein thrombosis (DVT) and pulmonary embolism (PE). Apixaban works by inhibiting Factor Xa, a key enzyme in the blood coagulation process.
The tablet is easy to administer and is typically taken twice daily, with or without food. Regular monitoring is not required, making it a convenient option for patients managing anticoagulation therapy.
Each film coated tablet contains:
Apixaban IH …………..2.5 mg
Excipients……………... Q.S
Oral
DOSAGE
As
directed by the physician.
• Increased risk of
Thrombotic events after premature discontinuation
• Bleeding
• Spinal/Epidural Anesthesia or Puncture
Premature discontinuation of any oral
anticoagulant, including LAVIXABAN, in the absence of
adequate alternative anticoagulation
increases the risk of thrombotic events. An increased rate
of stroke was observed during the transition
from LAVIXABAN to warfarin in clinical trials in atrial
fibrillation patients. If LAVIXABAN is
discontinued for a reason other than pathological bleeding
or completion of a course of therapy,
consider coverage with another anticoagulant.
Concomitant
use of drugs affecting hemostasis increases the risk of bleeding. These include
aspirin
and other antiplatelet agents, other anticoagulants, heparin, thrombolytic
agents, selective
serotonin
reuptake inhibitors, serotonin norepinephrine reuptake inhibitors, and
nonsteroidal anti-
inflammatory
drugs (NSAIDs)
Advise
patients of signs and symptoms of blood loss and to report them immediately or
go to an
emergency
room. Discontinue LAVIXABAN in patients with active pathological hemorrhage.
Direct-acting oral anticoagulants (DOACs), including LAVIXABAN, are not recommended for use
in patients with triple-positive antiphospholipid syndrome (APS). For patients with APS (especially
those who are triple positive [positive
for lupus anticoagulant, anticardiolipin, and anti–beta 2-
glycoprotein I antibodies]), treatment
with DOACs has been associated with increased rates of
recurrent thrombotic events compared
with vitamin K antagonist therapy.
6 x
10 Tablets