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    SECNIDAZOLE

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SECNIDAZOLE TABLETS 1 G


Urethritis and vaginitis due to Trichomonas vaginalis. Intestinal amebiasis. Hepatic amebiasis. Giardiasis.




COMPOSITION

Secnidazole …. 1 g

Excipients … q.s


Method of administration: Oral use.

DOSAGE

Urethritis and vaginitis due to Trichomonas vaginalis Adults: 2 g taken as a single dose at the beginning of a meal. Intestinal amebiasis Symptomatic acute amebiasis (E.histolytica form) Adults: 2 g taken as a single dose at the beginning of a meal. Children: 30 mg/kg/day taken as a single dose. Duration of treatment: one day only. Asymptomatic amebiasis (minuta and cyst forms): same daily dose for 3 days. Hepatic amebiasis Adults: 1.5 g daily taken as one or several doses at the beginning of a meal for 5 days. Children: 30 mg/kg/day taken as one or several doses at the beginning of a meal for 5 days.



SIDE EFFECT
The undesirable effects that may be observed are those of imidazole derivatives: 
∙ most frequently: gastrointestinal disorders with gastric pain, taste alteration (metallic taste), glossitis, stomatitis, 
∙ moderate leukopenia, reversible on treatment discontinuation, 
∙ rarely: dizziness, coordination disorders and ataxia, paresthesia, sensorimotor polyneuropathy.

The following have been reported with secnidazole: 
∙ rare gastrointestinal disorders (nausea, vomiting, gastric pain), 
∙ rare immediate hypersensitivity reactions: fever, erythema, urticaria and angioedema.




PRECAUTION
Drinking alcoholic beverages should be avoided during treatment with secnidazole. - This medicine should not be administered in patients with a history of blood dyscrasia. - This medicinal product can be administered in patients with celiac disease. Wheat starch can contain gluten, but only traces, and is therefore considered safe for patients with celiac disease.


PRESENTATION
Secnidazole Tablet are available in Alu-PVC blister pack of 2 tablets.