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    LIDOCAINE INJECTION

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The content or product detailing is not intended to replace advice from your prescribing doctor or healthcare professional. Lavina Pharma is not responsible for such actions by consumers. For any further information about the product please contact +91 22 2783 1455 and we can provide you the details.

LIDOCAINE INJECTION BP 2%


Lidocaine is a local anaesthetic of the amide group. Lidocaine Hydrochloride Injection BP is for use in infiltration anaesthesia, intravenous regional anaesthesia and nerve blocks.



COMPOSITION

Each ml contains:
Lidocaine Hydrochloride        BP    20 mg
Propyl paraben                         BP    0.2 mg (As preservative)
Methyl paraben                        BP    1 mg (As preservative)
Water for injection                   BP    q.s

The method of administration of lidocaine varies according to the procedure (infiltration anaesthesia, intravenous regional anaesthesia or nerve block).

DOSAGE

The dosage should be adjusted according to the response of the patient and the site of administration. The lowest concentration and smallest dose producing the required effect should be given. The maximum dose for healthy adults should not exceed 200 mg [or 500mg if given in solutions containing adrenaline (epinephrine)].

Children and elderly or debilitated patients require smaller doses, commensurate with age & physical status.

SIDE EFFECT
In common with other local anaesthetics, adverse reactions to Lidocaine are rare and are usually the result of raised plasma concentrations due to accidental intravascular injection, excessive dosage or rapid absorption from highly vascular areas, or may result from a hypersensitivity, idiosyncrasy or diminished tolerance on the part of the patient.
Systemic toxicity mainly involves the central nervous system and/or the cardiovascular system.
Immune system disorders
Hypersensitivity reactions (allergic or anaphylactoid reactions, anaphylactic shock) 
Nervous & Psychiatric disorders
Neurological signs of systemic toxicity include dizziness or light-headedness, nervousness, tremor, circumoral paraesthesia, tongue numbness, drowsiness, convulsions, coma.
Eye disorders
Blurred vision, diplopia and transient amaurosis may be signs of lidocaine toxicity.
Ear and labyrinth disorders
Tinnitus, hyperacusis
Cardiac and vascular disorders
Cardiovascular reactions are depressant and may manifest as hypotension, bradycardia, myocardial depression, cardiac arrhythmias and possibly cardiac arrest or circulatory collapse.
Respiratory, thoracic or mediastinal disorders
Dyspnoea, bronchospasm, respiratory depression, respiratory arrest
Gastrointestinal disorders
Nausea, vomiting
Skin & subcutaneous tissue disorders
Rash, urticaria, oedema (including angioedema, face oedema)
Blood and the lymphatic system disorders
Methaemoglobinaemia.




PRECAUTION
As with other local anaesthetics, Lidocaine should be used with caution in patients with epilepsy, myasthenia gravis, cardiac conduction disturbances, congestive heart failure, bradycardia, severe shock, impaired respiratory function or impaired renal function with a creatinine clearance of less than 10mL/minute.



PRESENTATION
Lidocaine Injection is available in 20 ml vial.