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LAVIXABAN is indicated to reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation.
Prophylaxis of deep vein thrombosis hip
or knee replacement surgery.
LAVIXABAN 5 is an anticoagulant medication that contains 5 mg of apixaban, designed to help prevent stroke and blood clots in patients with non-valvular atrial fibrillation.
It also treats and prevents deep vein thrombosis (DVT) and pulmonary embolism (PE). Apixaban works by selectively inhibiting Factor Xa, a crucial component in the blood clotting process.
The tablets are convenient to take, usually prescribed twice daily, with or without food. This formulation offers effective anticoagulation without the need for regular blood monitoring
Each film coated tablet contains:
Apixaban IH …………..5 mg
Excipients……………... Q.S
Oral
DOSAGE
As
directed by the physician.
• Increased risk of
Thrombotic events after premature discontinuation
• Bleeding
• Spinal/Epidural Anesthesia or Puncture
Premature
discontinuation of any oral anticoagulant, including LAVIXABAN, in the absence
of
adequate alternative anticoagulation
increases the risk of thrombotic events. An increased rate
of stroke was observed during the transition
from LAVIXABAN to warfarin in clinical trials in atrial
fibrillation patients. If LAVIXABAN is
discontinued for a reason other than pathological bleeding
or completion of a course of therapy,
consider coverage with another anticoagulant.
Concomitant
use of drugs affecting hemostasis increases the risk of bleeding. These include
aspirin
and other antiplatelet agents, other anticoagulants, heparin, thrombolytic
agents, selective
serotonin
reuptake inhibitors, serotonin norepinephrine reuptake inhibitors, and
nonsteroidal anti-
inflammatory
drugs (NSAIDs)
Advise
patients of signs and symptoms of blood loss and to report them immediately or
go to an
emergency
room. Discontinue LAVIXABAN in patients with active pathological hemorrhage.
Direct-acting oral anticoagulants
(DOACs), including LAVIXABAN, are not recommended for use
in patients with triple-positive
antiphospholipid syndrome (APS). For patients with APS (especially
those who are triple positive [positive
for lupus anticoagulant, anticardiolipin, and anti–beta 2-
glycoprotein I antibodies]), treatment
with DOACs has been associated with increased rates of
recurrent thrombotic events compared
with vitamin K antagonist therapy.
6 x
10 Tablets