METRONIDAZOLE INJECTION USP 500 MG / 100 ML
Metronidazole Injection is used in treatment of severe intraabdominal and gynaecological infections in which sensitive anaerobic bacteria particularly Bacteriodes and anaerobic Streptococci have been identified or are suspected to be the cause. The solution may also be used in combination with an antibiotic active against aerobic bacteria.
Each 100 ml contains:
Metronidazole USP … 500mg
Sodium chloride USP … 800mg
Water for injection USP … Q.s
Treatment of Anaerobic Bacterial Infections The recommended dosage schedule for adults is:
|Loading Dose||15 mg/kg infused over one hour (approximately 1 g for a 70-kg adult)|
|Maintenance Dose||7.5 mg/kg infused over one hour every six hours (approximately 500 mg for a 70-kg adult). The first maintenance dose should be instituted six hours following the initiation of the loading dose.|
Parenteral therapy may be changed to oral metronidazole when conditions warrant, based upon the severity of the disease and the response of the patient to Metronidazole Injection, USP treatment.